Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287453 | 0.86 | KMT2A (0.50) | LMNATP53RXFP1HCAR1KMT2A | |
| SCHEMBL30716464 | 0.85 | KMT2A (0.42) | KMT2AGRM1KDM4ESMN1; SMN2 | |
| SCHEMBL30716461 | 0.85 | RAB9A (0.42) | LMNATP53KMT2AGRM1THRB | |
| SCHEMBL30716453 | 0.85 | ALDH1A1 (0.40) | GRM1SMN1; SMN2CA1CA2CA4 | |
| SCHEMBL30716458 | 0.85 | XDH (0.41) | HCAR1KMT2AGRM1SMN1; SMN2CA1 | |
| SCHEMBL30716452 | 0.84 | FGFR1 (0.44) | LMNATP53KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30716459 | 0.84 | POLB (0.45) | LMNATP53RXFP1THRB | |
| SCHEMBL30716455 | 0.83 | KMT2A (0.47) | LMNAKMT2AGRM1THRBGAA | |
| SCHEMBL30716463 | 0.81 | ALDH1A1 (0.50) | TP53HCAR1GRM1THRBCA1 | |
| SCHEMBL30716516 | 0.81 | KDM4E (0.54) | LMNATP53RXFP1KMT2AGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343046-A | Novel 3-oxo-4-substituted aryl-3, 4-dihydropyrazine-2-carboxamide compound and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | claimed |
| CN-117343046-A | Novel 3-oxo-4-substituted aryl-3, 4-dihydropyrazine-2-carboxamide compound and application thereof | 辽宁大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-114787144-A | Pyridone compounds and methods for modulating protein kinases | 埃克塞里艾克西斯公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-101522687-A | Heterobicyclic thiophene compounds and methods of use | ARRAY BIOPHARMA INC (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101437820-A | Heterobicyclic pyrazole compounds and methods of use | ARRAY BIOPHARMA INC (US) | 2009-05-20 | — | — | CN | disclosed |