Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159378 | 0.98 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL25237284 | 0.84 | MEN1 (0.39) | TSHRALDH1A1MEN1KMT2A | |
| Acetic Acid SCHEMBL28158415 | 0.82 | THRB (0.48) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL8940602 | 0.81 | ALDH1A1 (0.35) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL33780 | 0.81 | THRB (0.52) | TSHRALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL11127704 | 0.81 | ALDH1A1 (0.59) | TSHRALDH1A1MEN1KMT2ATHRB | |
| Methacrylic Acid SCHEMBL9453881 | 0.80 | THRB (0.47) | TSHRALDH1A1MEN1KMT2ATHRB | |
| Methacrylic Acid SCHEMBL10424224 | 0.80 | THRB (0.47) | TSHRALDH1A1MEN1KMT2ATHRB | |
| Potassium Ion SCHEMBL752380 | 0.79 | ALDH1A1 (0.34) | TSHRALDH1A1MEN1KMT2A | |
| Carbamic Acid SCHEMBL28329175 | 0.79 | THRB (0.46) | TSHRALDH1A1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8003459-A | — | — | None | — | — | JP | disclosed |
| WO-2010132598-A1 | HETEROARYL COMPOUNDS AS PIKK INHIBITORS | AMGEN INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| JP-H083459-A | FINE HIGH-PERMITTIVITY ORGANIC POLYMER PARTICLE, ITS PRODUCTION, AND HIGH-PERMITTIVITY ORGANIC POLYMER MATERIAL | NIPPON KASEI CHEM CO LTD | 1996-01-09 | — | — | JP | disclosed |