Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763523 | 0.91 | MAPT (0.51) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27763515 | 0.90 | DHODH (0.53) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27742880 | 0.90 | DHODH (0.46) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27742882 | 0.87 | DHODH (0.48) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27742884 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1L3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL27742881 | 0.85 | MAPT (0.52) | ALDH1A1KDM4EHPGDPOLBMAPT | |
| SCHEMBL27763531 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27742923 | 0.82 | POLB (0.47) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27763530 | 0.82 | PARP1 (0.47) | ALDH1A1KDM4EHPGDPOLBPKM | |
| SCHEMBL27763517 | 0.82 | DHODH (0.45) | ALDH1A1KDM4EHPGDPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |