Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763531 | 0.92 | ALDH1A1 (0.52) | PARP1DHODHALDH1A1NPC1RAB9A | |
| SCHEMBL27742882 | 0.90 | DHODH (0.48) | PARP1GRM5DHODHALDH1A1NPC1 | |
| SCHEMBL27763517 | 0.90 | DHODH (0.45) | PARP1DHODHALDH1A1NPC1RAB9A | |
| SCHEMBL27742923 | 0.90 | POLB (0.47) | PARP1DHODHALDH1A1NPC1RAB9A | |
| SCHEMBL27742878 | 0.88 | PARP1 (0.48) | PARP1GRM5DHODHALDH1A1NPC1 | |
| SCHEMBL27742890 | 0.88 | MAPT (0.49) | PARP1GRM5DHODHALDH1A1NPC1 | |
| SCHEMBL27763519 | 0.88 | PARP1 (0.47) | PARP1GRM5DHODHALDH1A1NPC1 | |
| SCHEMBL27763510 | 0.86 | PARP1 (0.51) | PARP1DHODHALDH1A1NPC1RAB9A | |
| SCHEMBL27742883 | 0.84 | MMP2 (0.50) | PARP1GRM5DHODHRAB9ASMN1; SMN2 | |
| SCHEMBL27763516 | 0.83 | RAB9A (0.51) | PARP1GRM5DHODHALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |