Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27763511 | 0.90 | ALDH1A1 (0.53) | DHODHMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27763523 | 0.89 | MAPT (0.51) | DHODHMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27742889 | 0.88 | DHODH (0.46) | DHODHMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL27763532 | 0.88 | PTGES (0.46) | DHODHMAPTAKR1C3HTTPKN1 | |
| SCHEMBL27763520 | 0.85 | DHODH (0.48) | DHODHMAPTPKN1PKN2POLB | |
| SCHEMBL27742881 | 0.83 | MAPT (0.52) | DHODHMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27742871 | 0.80 | DHODH (0.44) | DHODHMAPTHSD17B10AKR1C3ALDH1A1 | |
| SCHEMBL27763513 | 0.80 | MMP2 (0.43) | DHODHMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27742876 | 0.80 | PARP1 (0.46) | DHODHCYP1A2CYP2C19AKR1C3HPGD | |
| SCHEMBL27742873 | 0.80 | DHODH (0.49) | DHODHMAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101434601-A | 2-furyl-1H-benzimidazole-4-acidamide type derivative | UNIV SHANGHAI JIAOTONG (CN) | 2009-05-20 | — | — | CN | disclosed |