Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 3/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL951017 | 0.77 | PRMT6 (0.39) | LMNAIDH1IDH2PRMT6NPC1 | |
| SCHEMBL21165939 | 0.76 | IDH1 (0.39) | LMNAIDH1IDH2PRMT6NPC1 | |
| SCHEMBL2528824 | 0.73 | PRMT6 (0.38) | LMNAIDH1IDH2PRMT6NPC1 | |
| SCHEMBL2766709 | 0.70 | PRMT6 (0.36) | IDH1IDH2PRMT6NPC1RAB9A | |
| SCHEMBL950089 | 0.68 | LMNA (0.45) | LMNAIDH1IDH2PRMT6AR | |
| SCHEMBL27216386 | 0.68 | CES1 (0.44) | LMNANPC1RAB9ANPSR1MAPT | |
| SCHEMBL26846624 | 0.66 | — | — | |
| SCHEMBL21166074 | 0.66 | — | — | |
| SCHEMBL23890516 | 0.66 | HCRTR1 (0.30) | — | |
| SCHEMBL2764434 | 0.66 | PRMT6 (0.36) | IDH1IDH2PRMT6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437921-A | Electroluminescent bis-cyclometallated iridium compounds and devices made with such compounds | DU PONT (US) | 2009-05-20 | — | — | CN | disclosed |