Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26846624 | 0.82 | — | — | |
| SCHEMBL951017 | 0.82 | PRMT6 (0.39) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL2766709 | 0.82 | PRMT6 (0.36) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL2764434 | 0.77 | PRMT6 (0.36) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL28051010 | 0.76 | ALDH1A1 (0.41) | PRMT6NPC1RAB9AMAPTPTGS1 | |
| SCHEMBL21165939 | 0.73 | IDH1 (0.39) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL27763596 | 0.73 | LMNA (0.38) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL23421840 | 0.71 | PRMT6 (0.38) | PRMT6NPC1RAB9AMAPTIDH1 | |
| SCHEMBL20483217 | 0.71 | — | — | |
| SCHEMBL5139434 | 0.71 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202932-A1 | METHODS FOR INHIBITING NEURON APOPTOSIS AND NECROSIS | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2017-07-20 | — | — | US | claimed |
| US-20150190366-A1 | METHODS FOR INHIBITING NEURON APOPTOSIS AND NECROSIS | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2015-07-09 | — | — | US | claimed |
| WO-2014005186-A1 | METHODS FOR INHIBITING NEURON APOPTOSIS AND NECROSIS | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2014-01-09 | — | — | WO | claimed |
| US-20020091268-A1 | Pyrazolate copper complexes, and MOCVD of copper using same | XU CHONGYING (US) | 2002-07-11 | — | — | US | claimed |
| WO-2001068948-A1 | PYRAZOLATE COPPER COMPLEXES, AND MOCVD OF COPPER USING SAME | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |
| US-12544371-B2 | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome | CALCIMEDICA, INC. (US) | 2026-02-10 | — | — | US | disclosed |
| US-20250120969-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | AVENUE CAPITAL MANAGEMENT II, L.P. | 2025-04-17 | — | — | US | disclosed |
| EP-4465988-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | Calcimedica, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023141523-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | CALCIMEDICA, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| US-20230120819-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | AVENUE CAPITAL MANAGEMENT II, L.P. | 2023-04-20 | — | — | US | disclosed |
| EP-4121089-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | Calcimedica, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021189013-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | CALCIMEDICA, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2009095719-A2 | TREATMENT OF MAST CELL RELATED DISORDERS | ISIS INNOVATION LIMITED (GB) | 2009-08-06 | — | — | WO | disclosed |
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-11-22 | — | — | US | disclosed |
| US-6639080-B2 | Reacting bis(trifluoromethyl)pyrazole with a stoichiometric excess of copper oxide(Cu2O) and recovering bis(trifluoromethyl)pyrazolyl copper, or adding Lewis base ligand to form an adduct of above and Lewis base | ADVANCED TECHNOLOGY MATERIALS, INC. | 2003-10-28 | — | — | US | disclosed |
| US-6440202-B1 | METALORGANIC CHEMICAL VAPOR DEPOSITION (MOCVD); REDUCED OXY CONTENT, OR OXYGEN-FREE; FOR LIQUID DELIVERY OF CVD COPPER; GOOD ADHESION AND ELECTROCONDUCTIVITY | ADVANCED TECHNOLOGY MATERIALS, INC. | 2002-08-27 | — | — | US | disclosed |
| US-20020091268-A1 | Pyrazolate copper complexes, and MOCVD of copper using same | XU CHONGYING (US) | 2002-07-11 | — | — | US | disclosed |
| US-6417369-B1 | LEWIS ACID ADDUCTS; SEMICONDUCTORS, INTEGRATED CIRCUITS; THIN FILM RECORDING HEAD | ADVANCED TECHNOLOGY MATERIALS, INC. | 2002-07-09 | — | — | US | disclosed |
| US-20020042518-A1 | Pyrazolate copper complexes, and MOCVD of copper using same | XU CHONGYING (US) | 2002-04-11 | — | — | US | disclosed |
| WO-2001068948-A1 | PYRAZOLATE COPPER COMPLEXES, AND MOCVD OF COPPER USING SAME | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | ORC3, AP3M1, PUF60 | PRMT6 3930/4885NPC1 3670/4885RAB9A 1969/4885 |
| US-20020042518-A1 | Pyrazolate copper complexes, and MOCVD of copper using same | SOD1, JUND, AOC1 | PRMT6 3790/4885NPC1 4484/4885RAB9A 1419/4885 |
| US-12544371-B2 | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome | ORAI1, MAVS, CASR | PRMT6 2352/4885NPC1 3859/4885RAB9A 586/4885 |
| US-20020091268-A1 | Pyrazolate copper complexes, and MOCVD of copper using same | SOD1, JUND, AOC1 | PRMT6 3790/4885NPC1 4484/4885RAB9A 1419/4885 |
| US-20250120969-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | IL1B, MAVS, MMP8 | PRMT6 2577/4885NPC1 4241/4885RAB9A 1122/4885 |
| US-20230120819-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | MAVS, ATF1, IL1B | PRMT6 2645/4885NPC1 4239/4885RAB9A 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.