Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665063 | 0.84 | GPR84 (0.50) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL27500637 | 0.82 | GRM8 (0.48) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL27524118 | 0.82 | GRM8 (0.48) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL857209 | 0.82 | MET (0.56) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL27785916 | 0.81 | GRM8 (0.47) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL30713622 | 0.81 | GPR84 (0.46) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL12491066 | 0.79 | AXL (0.51) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL858688 | 0.79 | MET (0.52) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL31358333 | 0.77 | GPR84 (0.43) | GPR84AXLGRM8GRM4MET | |
| SCHEMBL14663942 | 0.75 | AXL (0.47) | GPR84AXLGRM8GRM4MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101547909-A | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM INT (DE) | 2009-09-30 | — | — | CN | disclosed |