Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3585030 | 0.87 | TDP2 (0.37) | ERN1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL3583793 | 0.84 | ABCB1 (0.37) | DHODHKDM4EMEN1MAPTKMT2A | |
| SCHEMBL3583790 | 0.84 | ABCB1 (0.37) | DHODHKDM4EMEN1MAPTKMT2A | |
| SCHEMBL27764464 | 0.83 | CRHBP (0.38) | DHODHKDM4EMEN1MAPTKMT2A | |
| SCHEMBL27743608 | 0.82 | DHODH (0.38) | DHODHERN1KDM4EMEN1MAPT | |
| SCHEMBL3576357 | 0.81 | MAPT (0.41) | DHODHERN1KDM4EMEN1MAPT | |
| SCHEMBL27743599 | 0.80 | TTR (0.36) | ERN1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL27743583 | 0.80 | MAOA (0.36) | KDM4EMAPTTTRCRHBPCRHR2 | |
| SCHEMBL3584042 | 0.79 | DHODH (0.40) | DHODHERN1KDM4EMEN1MAPT | |
| SCHEMBL3591823 | 0.79 | CRHBP (0.47) | DHODHERN1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454285-B | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA | 2012-06-27 | — | — | CN | disclosed |
| CN-101454285-A | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA (PT) | 2009-06-10 | — | — | CN | disclosed |