Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | CCR1 | P32246 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775840 | 0.84 | CCR1 (0.45) | GPR119CCR1KCNH2TSHR | |
| SCHEMBL2774368 | 0.83 | EPHX2 (0.50) | CCR1KCNH2 | |
| SCHEMBL2775563 | 0.82 | PIK3CD (0.46) | GPR119 | |
| SCHEMBL2774679 | 0.82 | EPHX2 (0.51) | CCR1KCNH2 | |
| Hydrochloric Acid SCHEMBL2773474 | 0.81 | PIK3CD (0.45) | GPR119 | |
| SCHEMBL2776484 | 0.81 | KMT2A (0.41) | GPR119CCR1KCNH2 | |
| SCHEMBL2775696 | 0.80 | EPHX2 (0.53) | GPR119CCR1KCNH2TSHR | |
| SCHEMBL2775758 | 0.80 | ACACB (0.44) | GPR119CCR1 | |
| SCHEMBL2776334 | 0.79 | HMOX1 (0.53) | CCR1KCNH2 | |
| SCHEMBL2776637 | 0.79 | CCR1 (0.45) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |