SCHEMBL2775563

SCHEMBL2775563

Cc1nccnc1OC1CCN(C(=O)[C@@H](N)C(C)C)CC1

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.46
GPR119 Q8TDV5 8/20 0.44
DPP4 P27487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2773474 0.99 PIK3CD (0.45) PIK3CDGPR119DPP4
SCHEMBL2776473 0.82 GPR119 (0.44) GPR119
Hydrochloric Acid SCHEMBL2774408 0.81 HRH3 (0.43) PIK3CDGPR119
SCHEMBL6520086 0.80 GPR119 (0.39) GPR119
Hydrochloric Acid SCHEMBL2775529 0.79 EPHX2 (0.47) DPP4
Hydrochloric Acid SCHEMBL2773858 0.79 EPHX2 (0.48) PIK3CDGPR119
SCHEMBL2776779 0.76 GPR119 (0.46) PIK3CDGPR119
SCHEMBL2774207 0.76 NAMPT (0.49) PIK3CDGPR119
Hydrochloric Acid SCHEMBL2774913 0.76 HSD11B1 (0.47) PIK3CDGPR119DPP4
Hydrochloric Acid SCHEMBL2773533 0.75 GPR119 (0.45) PIK3CDGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258697-A1 HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2010-12-08 EP disclosed