Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 9/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775696 | 0.85 | EPHX2 (0.53) | EPHX2NAMPTALDH1A1CCR1KCNH2 | |
| SCHEMBL2780460 | 0.83 | NAMPT (0.49) | ACACBNAMPTCCR1KCNH2 | |
| SCHEMBL2776473 | 0.82 | GPR119 (0.44) | CCR1KCNH2 | |
| SCHEMBL2777086 | 0.82 | EPHX2 (0.53) | EPHX2NAMPTALDH1A1CCR1KCNH2 | |
| Hydrochloric Acid SCHEMBL2773858 | 0.81 | EPHX2 (0.48) | EPHX2CYP2C9NAAAACACBNAMPT | |
| SCHEMBL2774368 | 0.81 | EPHX2 (0.50) | EPHX2CYP2C9ACACBNAMPTALDH1A1 | |
| SCHEMBL2776856 | 0.81 | MMP1 (0.59) | NAMPTCCR1KCNH2 | |
| SCHEMBL2776032 | 0.81 | NAMPT (0.50) | EPHX2CYP2C9NAMPTCCR1 | |
| SCHEMBL2774593 | 0.81 | EPHX2 (0.46) | EPHX2CYP2C9NAAANAMPTALDH1A1 | |
| SCHEMBL2777388 | 0.80 | KMT2A (0.43) | NAMPTCCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |