Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | METAP1 | P53582 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108672 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EMAPTTDP1PARP1 | |
| SCHEMBL3441534 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTTDP1PARP1 | |
| SCHEMBL5279227 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1PARP1LMNA | |
| SCHEMBL69045 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTTDP1LMNA | |
| SCHEMBL344528 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1PARP1LMNA | |
| SCHEMBL28229068 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTTDP1PARP1 | |
| SCHEMBL29749881 | 0.78 | PARP1 (0.70) | ALDH1A1KDM4EMAPTTDP1PARP1 | |
| SCHEMBL111826 | 0.78 | PARP1 (0.70) | ALDH1A1KDM4EMAPTTDP1PARP1 | |
| SCHEMBL22918322 | 0.78 | EGLN1 (0.74) | ALDH1A1TDP1PARP1LMNAMETAP2 | |
| SCHEMBL10900815 | 0.78 | ALDH1A1 (0.63) | ALDH1A1KDM4EMAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107522697-B | Pyrroles [2,1-a] morphinane alkaloid and its preparation method and application | 许昌学院 | 2019-11-12 | — | — | CN | disclosed |
| CN-107522697-A | Pyrroles [2,1 a] morphinane alkaloid and its preparation method and application | 许昌学院 | 2017-12-29 | — | — | CN | disclosed |
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |