Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765143 | 0.86 | RAB9A (0.58) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL6640141 | 0.81 | RAB9A (0.56) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL112702 | 0.77 | POLB (0.50) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EHTT | |
| SCHEMBL10846214 | 0.77 | KMT2A (0.53) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL489903 | 0.76 | RAB9A (0.62) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL27787217 | 0.73 | HPGD (0.74) | HPGDSMN1; SMN2ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL604508 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL8139581 | 0.71 | HSP90AA1 (0.54) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL17548441 | 0.70 | KMT2A (0.78) | HPGDALDH1A1HTTMEN1CYP1A2 | |
| SCHEMBL26421854 | 0.70 | DAO (0.54) | HPGDSMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597263-A | Preparation of novel S-DABO HIV-1 reverse transcriptase inhibitor and uses thereof | UNIV CAPITAL MEDICAL (CN) | 2009-12-09 | — | — | CN | disclosed |