Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | PPARG | P37231 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.78 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.78 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.72 |
| ▸ | KDM1A | O60341 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16772489 | 0.86 | KMT2A (0.95) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17548498 | 0.84 | ACMSD (1.00) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16772545 | 0.76 | MEN1 (0.69) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23892607 | 0.76 | ACMSD (0.79) | KMT2AMEN1ALDH1A1HPGDPPARG | |
| SCHEMBL6218562 | 0.75 | KMT2A (0.76) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16772559 | 0.74 | KMT2A (0.71) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16772582 | 0.71 | MEN1 (0.65) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29114049 | 0.70 | ACMSD (0.68) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30613089 | 0.70 | ACMSD (0.68) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27765197 | 0.70 | HPGD (0.48) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186242-B1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S R L (IT) | 2021-10-06 | — | — | EP | disclosed |
| US-20170362185-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2017-12-21 | — | — | US | disclosed |
| US-9708272-B2 | Inhibitors of α-amino-β-carboxymuconic acid semialdehyde decarboxylase | TES PHARMA S.R.L. (IT) | 2017-07-18 | — | — | US | disclosed |
| US-20160060226-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060226-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | KMT2A 1353/4885MEN1 2572/4885CYP1A2 1119/4885 |
| US-20170362185-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | KMT2A 1353/4885MEN1 2572/4885CYP1A2 1119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.