Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 12/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765096 | 0.90 | NR1H2 (0.41) | NR1H2NR1H3ESR1ENPP1 | |
| SCHEMBL28780850 | 0.89 | NR1H2 (0.41) | NR1H2NR1H3DDR1RORCESR1 | |
| SCHEMBL27786978 | 0.83 | KDM4E (0.43) | NR1H2NR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL4165443 | 0.80 | NR1H2 (0.44) | NR1H2NR1H3CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4166161 | 0.79 | NR1H2 (0.46) | NR1H2NR1H3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4165449 | 0.79 | NR1H2 (0.44) | NR1H2NR1H3 | |
| SCHEMBL27765402 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3KDM4EALDH1A1HPGD | |
| SCHEMBL4166168 | 0.76 | NR1H2 (0.48) | NR1H2NR1H3RORC | |
| SCHEMBL4162283 | 0.75 | NR1H2 (0.41) | NR1H2NR1H3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28780848 | 0.75 | NR1H2 (0.39) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | claimed |
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |