Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080326 | 0.83 | KMT2A (0.44) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL362137 | 0.80 | KMT2A (0.49) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL1711707 | 0.78 | KMT2A (0.41) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL27635826 | 0.77 | ALDH1A1 (0.36) | KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL521187 | 0.77 | PKM (0.53) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL12633753 | 0.75 | KMT2A (0.64) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL1856233 | 0.75 | ALDH1A1 (0.51) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL1026370 | 0.74 | KMT2A (0.44) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL3375617 | 0.74 | PKM (0.39) | KMT2APKMLMNAMEN1GAA | |
| SCHEMBL369546 | 0.74 | PKM (0.39) | KMT2APKMLMNAMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541756-A | Pyrazoles as glucokinase activators | HOFFMANN LA ROCHE (CH) | 2009-09-23 | — | — | CN | disclosed |