SCHEMBL1856233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL521187	0.86	PKM (0.53)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL25305914	0.85	LMNA (0.43)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL11016950	0.83	ALDH1A1 (0.55)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL10264585	0.81	LMNA (0.46)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL10732353	0.79	POLB (0.59)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL1862488	0.78	ALDH1A1 (0.35)	ALDH1A1LMNAPOLBKMT2AMEN1
	SCHEMBL31105872	0.77	ALDH1A1 (0.49)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL1861031	0.76	LMNA (0.47)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL362137	0.76	KMT2A (0.49)	ALDH1A1LMNAPOLBKMT2APKM
	SCHEMBL31052675	0.75	ALDH1A1 (0.50)	ALDH1A1LMNAPOLBKMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.