Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780715 | 0.92 | NOTUM (0.34) | NOTUMHSD11B1NR1H2NR1H3 | |
| SCHEMBL27744707 | 0.88 | NOTUM (0.36) | NOTUM | |
| SCHEMBL27744699 | 0.87 | NOTUM (0.44) | NOTUMHSD11B1NR1H2NR1H3 | |
| SCHEMBL27744690 | 0.85 | NOTUM (0.43) | NOTUMHSD11B1NR1H2NR1H3 | |
| SCHEMBL1470445 | 0.84 | NOTUM (0.47) | NOTUMHSD11B1 | |
| SCHEMBL1470442 | 0.84 | NOTUM (0.47) | NOTUMHSD11B1 | |
| SCHEMBL27765595 | 0.80 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL27765691 | 0.79 | NOTUM (0.36) | NOTUMNR1H2NR1H3 | |
| SCHEMBL20309058 | 0.78 | NOTUM (0.49) | NOTUMHSD11B1NR1H2NR1H3 | |
| SCHEMBL27765780 | 0.77 | NR1H2 (0.35) | NOTUMHSD11B1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421258-B | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYPSYS INC | 2013-08-21 | — | — | CN | disclosed |
| CN-101421258-A | Sulfonyl-substituted bicyclic compounds as PPAR modulators | KALYSPSYS INC (US) | 2009-04-29 | — | — | CN | disclosed |