Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27918000 | 0.84 | MC4R (0.53) | SIGMAR1HRH2LMNAMC4RPOLB | |
| SCHEMBL64954 | 0.82 | SIGMAR1 (0.64) | SIGMAR1HRH2LMNAPOLB | |
| SCHEMBL4752402 | 0.81 | SIGMAR1 (0.51) | SIGMAR1LMNAPOLB | |
| SCHEMBL22208166 | 0.80 | GBA1 (0.50) | SIGMAR1ACHE | |
| SCHEMBL21704267 | 0.80 | SIGMAR1 (0.59) | SIGMAR1HRH2LMNAMC4RPOLB | |
| SCHEMBL27801284 | 0.79 | SIGMAR1 (0.49) | SIGMAR1LMNA | |
| SCHEMBL14528083 | 0.79 | HRH2 (0.66) | SIGMAR1HRH2LMNAMC4RPOLB | |
| SCHEMBL5692251 | 0.79 | HRH2 (0.66) | SIGMAR1HRH2LMNAMC4RPOLB | |
| SCHEMBL20284487 | 0.79 | HRH2 (0.66) | SIGMAR1HRH2LMNAMC4RPOLB | |
| SCHEMBL30724547 | 0.78 | SIGMAR1 (0.49) | SIGMAR1HRH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611014-B | Amidopyrazoles as FGFR inhibitors | ASTRAZENECA AB | 2012-05-30 | — | — | CN | disclosed |
| CN-101600698-B | Quinazolinone and isoquinolinone acetamide derivatives | ORGANON NV | 2012-01-11 | — | — | CN | disclosed |
| CN-101611014-A | Amidopyrazoles as FGFR inhibitors | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | CN | disclosed |
| CN-101600698-A | Quinazolinone and isoquinolinone acetamide derivatives | ORGANON NV (NL) | 2009-12-09 | — | — | CN | disclosed |