Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289858 | 0.87 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3IDO1CHRNB2 | |
| SCHEMBL2701985 | 0.87 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3IDO1CHRNB2 | |
| SCHEMBL20837459 | 0.84 | FFAR1 (0.46) | SLC6A4HTR1ASLC6A2SLC6A3CHRNB2 | |
| SCHEMBL14342059 | 0.84 | SMN1; SMN2 (0.49) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL12260703 | 0.82 | CHRNB2 (0.41) | SLC6A4SLC6A2OPRM1SLC6A3IDO1 | |
| SCHEMBL31274209 | 0.82 | MAOB (0.46) | SLC6A4SLC6A2SLC6A3IDO1CHRNB2 | |
| SCHEMBL28488082 | 0.81 | CHRM2 (0.54) | SLC6A4CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL1947237 | 0.81 | MAOB (0.50) | IDO1HTR7HTR6MAOBSIGMAR1 | |
| SCHEMBL5855793 | 0.81 | CASR (0.46) | SLC6A4CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL5855802 | 0.81 | CASR (0.46) | SLC6A4CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101610995-A | Novel glucagon receptor antagonists | METABASIS THERAPEUTICS INC (US) | 2009-12-23 | — | — | CN | disclosed |