Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701985 | 0.87 | SLC6A2 (0.47) | MAPTL3MBTL1CHRNB2CHRNA4IDO1 | |
| SCHEMBL14289858 | 0.87 | SLC6A2 (0.47) | MAPTL3MBTL1CHRNB2CHRNA4IDO1 | |
| SCHEMBL14342059 | 0.84 | SMN1; SMN2 (0.49) | MAPTRAB9ASMN1; SMN2L3MBTL1CHRNB2 | |
| SCHEMBL20837459 | 0.84 | FFAR1 (0.46) | MAOBMAOAMAPTL3MBTL1CHRNB2 | |
| SCHEMBL12260703 | 0.82 | CHRNB2 (0.41) | CHRNB2CHRNA4IDO1TACR1FFAR1 | |
| SCHEMBL27765989 | 0.82 | SLC6A4 (0.44) | MAOBCHRNB2CHRNA4IDO1FFAR1 | |
| SCHEMBL6507492 | 0.79 | ESR1 (0.44) | MAPTCHRNB2CHRNA4IDO1TACR1 | |
| SCHEMBL20837528 | 0.78 | CHRNB2 (0.56) | MAOBCHRNB2CHRNA4IDO1TACR1 | |
| SCHEMBL12663141 | 0.78 | LPL (0.43) | CHRNB2CHRNA4FFAR1 | |
| SCHEMBL8145077 | 0.77 | IDO1 (0.47) | MAOBMAOAGAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727652-A1 | (HETERO)ARYL-SULFONAMIDE COMPOUNDS AS MODULATORS OF GPR35 | ThirtyFiveBio Limited (GB) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256827-A1 | (HETERO)ARYL-SULFONAMIDE COMPOUNDS AS MODULATORS OF GPR35 | ThirtyFiveBio Limited (GB) | 2024-12-19 | — | — | WO | disclosed |