SCHEMBL5855802

SCHEMBL5855802

CC(OCc1ccc(Br)cc1)c1ccc2ccccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASR P41180 3/20 0.46
UGT2B7 P16662 1/20 0.44
CYP2A6 P11509 2/20 0.42
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
AOC3 Q16853 2/20 0.40
HRH4 Q9H3N8 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
MAOB P27338 2/20 0.40
CYP1A2 P05177 2/20 0.39
MEN1 O00255 1/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 1/20 0.39
HIF1A Q16665 1/20 0.39
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5855793 1.00 CASR (0.46) CASRUGT2B7CYP2A6HTR2AHTR2C
SCHEMBL27765989 0.81 SLC6A4 (0.44) HTR2AMAOBMEN1KMT2ACHRM2
SCHEMBL26267221 0.76 ALOX5 (0.45) CASRAOC3MAOBCYP2D6SLC6A2
SCHEMBL11049839 0.76 UGT2B7 (0.53) CASRUGT2B7CYP2A6AOC3CYP1A2
SCHEMBL1947237 0.74 MAOB (0.50) MAOB
SCHEMBL17894204 0.73 SLC6A4 (0.47) HTR2AHTR2CHTR2BSLC6A4
SCHEMBL11050148 0.73 SLC6A2 (0.56) CASRUGT2B7AOC3CYP1A2MEN1
SCHEMBL14814416 0.72 UGT2B7 (0.49) CASRUGT2B7AOC3CYP1A2MEN1
SCHEMBL11765268 0.72 CASR (0.50) CASRUGT2B7AOC3CYP1A2MEN1
SCHEMBL11761172 0.72 UGT2B7 (0.49) CASRUGT2B7AOC3CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7001648-B2 Glassy chiral-nematic liquid crystals and optical devices containing same UNIVERSITY OF ROCHESTER (US) 2006-02-21 US disclosed
US-20050263741-A1 GLASSY CHIRAL-NEMATIC LIQUID CRYSTALS AND OPTICAL DEVICES CONTAINING SAME NATIONAL SCIENCE FOUNDATION 2005-12-01 US disclosed