Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083201 | 0.78 | NR1H4 (0.52) | MEN1KMT2AALDH1A1GAA | |
| SCHEMBL6328328 | 0.78 | LMNA (0.55) | KMT2AALDH1A1HPGDHDAC1HDAC2 | |
| SCHEMBL27766332 | 0.77 | KMT2A (0.45) | KMT2AALDH1A1GAAADORA3ADORA1 | |
| SCHEMBL27792725 | 0.76 | NR1H4 (0.49) | MEN1KMT2AALDH1A1GAAHDAC1 | |
| SCHEMBL16236486 | 0.75 | KDM4E (0.66) | KDM4EMEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL27341191 | 0.73 | ACACB (0.51) | KDM4EMEN1KMT2ABCHEACHE | |
| SCHEMBL6635027 | 0.72 | HPGD (0.54) | ALDH1A1HPGD | |
| SCHEMBL16756230 | 0.71 | KDM4E (0.75) | KDM4EMEN1RECQLKMT2A | |
| SCHEMBL6836201 | 0.71 | KMT2A (0.56) | KDM4EMEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL563342 | 0.71 | ALDH1A1 (0.73) | ALDH1A1GAAHPGDHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466714-A | Purinone derivatives as HM74A agonists | INCYTE CORP (US) | 2009-06-24 | — | — | CN | disclosed |