Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.41 |
| ▸ | WNT3A | P56704 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL22129287 | 0.89 | MAOB (0.44) | LMNAALOX12CTNNB1WNT3AMAOB | |
| SCHEMBL31681671 | 0.89 | MAOB (0.44) | LMNAALOX12CTNNB1WNT3AMAOB | |
| Benzofuran SCHEMBL29393518 | 0.86 | — | — | |
| Benzofuran SCHEMBL29415475 | 0.86 | — | — | |
| Benzofuran SCHEMBL3160534 | 0.86 | — | — | |
| Benzofuran SCHEMBL5834531 | 0.86 | MAOA (0.46) | LMNAALOX12ACHECTNNB1WNT3A | |
| Benzofuran SCHEMBL5564 | 0.86 | — | — | |
| Benzofuran SCHEMBL9735995 | 0.84 | MAOA (0.41) | LMNACTNNB1WNT3AMAOBMAOA | |
| Benzofuran SCHEMBL28153539 | 0.84 | MAOA (0.41) | LMNACTNNB1WNT3AMAOBMAOA | |
| Biphenyl SCHEMBL9641251 | 0.84 | ALDH1A1 (0.45) | LMNACTNNB1WNT3AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112675919-B | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzyl benzofuran compound | 苏州大学 | 2023-06-13 | — | — | CN | claimed |
| CN-112675919-A | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzylbenzofuran compounds | 苏州大学 | 2021-04-20 | — | — | CN | claimed |
| CN-112645909-A | Method for synthesizing alpha-benzyl benzofuran compound | 苏州大学 | 2021-04-13 | — | — | CN | claimed |
| CN-105732552-B | The preparation method of 2 or 3 thio benzofuran compounds | 天津师范大学 | 2017-12-01 | — | — | CN | claimed |
| CN-102229606-A | 2-methylbenzofuran derivative containing isoxazole heterocycle, and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2011-11-02 | — | — | CN | claimed |
| CN-112675919-B | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzyl benzofuran compound | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-112675919-B | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzyl benzofuran compound | 苏州大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-112675919-A | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzylbenzofuran compounds | 苏州大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-112675919-A | Application of N-heterocyclic carbene-based mixed nickel (II) complex in synthesis of alpha-benzylbenzofuran compounds | 苏州大学 | 2021-04-20 | — | — | CN | disclosed |
| CN-112645909-A | Method for synthesizing alpha-benzyl benzofuran compound | 苏州大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-105732552-B | The preparation method of 2 or 3 thio benzofuran compounds | 天津师范大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-102321204-B | Selenium resin load, and intermediate, preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2013-07-24 | — | — | CN | disclosed |
| CN-102267989-A | 2-methyl-benzofuran compounds and preparation and application thereof | — | 2011-12-07 | — | — | CN | disclosed |
| CN-102229606-A | 2-methylbenzofuran derivative containing isoxazole heterocycle, and preparation method and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2011-11-02 | — | — | CN | disclosed |
| CN-102229603-A | Triazole heterocycle-containing 2-methyl benzofuran compound, and preparation and application thereof | UNIV ZHEJIANG TECHNOLOGY | 2011-11-02 | — | — | CN | disclosed |
| CN-102083827-A | Thiazolidine compounds as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2011-06-01 | — | — | CN | disclosed |
| CN-101730696-A | 3-aza-bicyclo [3.3.0] octane compounds | ACTELION PHARMACEUTICALS LTD | 2010-06-09 | — | — | CN | disclosed |
| CN-101711247-A | 2-cyclopropyl-thiazole derivatives | ACTELION PHARMACEUTICALS LTD | 2010-05-19 | — | — | CN | disclosed |
| CN-101641342-A | Thiazolidine derivatives | ACTELION PHARMACEUTICAL LTD CH | 2010-02-03 | — | — | CN | disclosed |
| CN-101575266-A | Method for refining phenol by acid-treated aluminium cross-linked montmorillonite catalyst | UNIV BEIJING CHEMICAL (CN) | 2009-11-11 | — | — | CN | disclosed |