SCHEMBL27767641

SCHEMBL27767641

Cc1cc(C)cc(C)c1.O=CP(=O)(O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
ALOX15 P16050 1/20 0.52
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA5A P35218 1/20 0.45
CFTR P13569 1/20 0.41
HTT P42858 1/20 0.39
ACP3 P15309 1/20 0.39
ESR1 P03372 1/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
SRC P12931 1/20 0.37
TSPO P30536 1/20 0.37
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
PGK1 P00558 1/20 0.36
PGK2 P07205 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27416489 0.80 CA2 (0.38) TSHRALOX15CA2CA4CA5A
SCHEMBL27950797 0.80 CA2 (0.38) TSHRALOX15CA2CA4CA5A
SCHEMBL2470616 0.76 TSHR (0.56) TSHRALOX15CA2CA4CA5A
SCHEMBL27664138 0.74 HPGD (0.61) TSHRCA2CA4CA5ACFTR
M-Xylene SCHEMBL28754450 0.73 ACHE (0.46) TSHRCA2CA4CA5AHTT
SCHEMBL806050 0.72 TSHR (0.67) TSHRALOX15CA2CA4CA5A
SCHEMBL31212644 0.71 LMNA (0.47) TSHRCA2CA4CA5AHTT
SCHEMBL28136531 0.71 LMNA (0.47) TSHRCA2CA4CA5AHTT
Toluene SCHEMBL27338066 0.69 LMNA (0.48) TSHRALOX15CA2CA4CA5A
SCHEMBL15717372 0.69 TSHR (0.47) TSHRALOX15CA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103988313-A Method for manufacturing silicon substrate having textured structure TOKUYAMA CORPROATION 2014-08-13 CN disclosed
CN-100575044-C Produce the method for moulded parts, and the sheet material of coating BASF COATINGS AG 2009-12-30 CN disclosed