Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578647 | 0.88 | ALOX15 (0.41) | ALOX15KMT2AKDM4ERECQLRAB9A | |
| SCHEMBL28980518 | 0.79 | ALOX15 (0.46) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL29010036 | 0.77 | KMT2A (0.48) | ALOX15KMT2AKDM4EMEN1RECQL | |
| SCHEMBL1994064 | 0.76 | ALOX15 (0.49) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL22230490 | 0.76 | MRGPRX4 (0.44) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL2939435 | 0.74 | ALOX15 (0.47) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL7043280 | 0.74 | ALOX15 (0.47) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL27579984 | 0.73 | ALOX15 (0.40) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL11022534 | 0.73 | ALOX15 (0.49) | ALOX15BCL9CTNNB1KMT2AKDM4E | |
| SCHEMBL27740419 | 0.73 | ALOX15 (0.49) | ALOX15BCL9CTNNB1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101610764-B | Benzamide derivatives as EP4 receptor agonists | GLAXO GROUP LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-101610764-A | As EP 4The heterocyclic carbamate derivatives of receptor stimulating agent | GLAXO GROUP LTD (GB) | 2009-12-23 | — | — | CN | disclosed |