SCHEMBL29010036

SCHEMBL29010036

CCCCC(=O)Oc1ccc(F)c(Cl)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
ALOX15 P16050 2/20 0.44
POLM Q9NP87 1/20 0.39
POLK Q9UBT6 1/20 0.39
POLL Q9UGP5 1/20 0.39
POLH Q9Y253 1/20 0.39
TOP2A P11388 2/20 0.38
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTR7 P34969 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 1/20 0.36
HPGD P15428 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996406 0.86 KMT2A (0.51) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL29009874 0.82 KMT2A (0.48) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL29009835 0.79 MEN1 (0.55) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL28980518 0.79 ALOX15 (0.46) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1996651 0.79 KDM4E (0.57) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL15548006 0.77 ALOX15 (0.57) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL27767643 0.77 ALOX15 (0.43) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL1994064 0.76 ALOX15 (0.49) KMT2AKDM4EMEN1RECQLALOX15
SCHEMBL27905805 0.76 CYP4F2 (0.47) KMT2AKDM4EMEN1ALDH1A1TDP1
SCHEMBL1997560 0.76 KMT2A (0.54) KMT2AKDM4EMEN1RECQLALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed