Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922850 | 0.85 | ALDH1A1 (0.48) | ALDH1A1RAB9AMEN1NPC1KMT2A | |
| SCHEMBL2755400 | 0.85 | ALDH1A1 (0.56) | ALDH1A1POLBRAB9AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL10354232 | 0.83 | ALDH1A1 (0.54) | ALDH1A1POLBRAB9AMEN1NPC1 | |
| SCHEMBL5518254 | 0.82 | NPSR1 (0.63) | LTB4RNPSR1POLBAPEX1MEN1 | |
| SCHEMBL10784805 | 0.81 | NPSR1 (0.47) | LTB4RNPSR1POLBAPEX1ELANE | |
| SCHEMBL3692519 | 0.80 | NPSR1 (0.50) | NPSR1ALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL14110381 | 0.80 | NPSR1 (0.55) | NPSR1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL28123366 | 0.80 | POLB (0.54) | NPSR1ALDH1A1POLBHSD17B10KDM4E | |
| SCHEMBL27768217 | 0.80 | LTB4R (0.39) | LTB4RALDH1A1POLBRAB9AMEN1 | |
| SCHEMBL17058903 | 0.79 | ACE2 (0.53) | ALDH1A1POLBRAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563347-A | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2009-10-21 | — | — | CN | disclosed |