Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496115 | 0.86 | EPHX2 (0.48) | ACE2ALDH1A1MEN1KMT2AEPHX2 | |
| SCHEMBL27893911 | 0.84 | MTNR1A (0.39) | LTB4RACE2EPHX2ELANEPLA2G2D | |
| SCHEMBL14110364 | 0.82 | CYP4F2 (0.41) | CYP4F2CYP4A11 | |
| SCHEMBL14110319 | 0.82 | EGFR (0.40) | CYP4F2CYP4A11POLB | |
| SCHEMBL27768215 | 0.80 | LTB4R (0.50) | LTB4RALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL28781347 | 0.79 | PLA2G2D (0.52) | LTB4RALDH1A1PLA2G2DTSHRPOLB | |
| SCHEMBL8439136 | 0.79 | CYP4F2 (0.53) | ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL3211949 | 0.78 | ALDH1A1 (0.35) | LTB4RALDH1A1EPHX2PLA2G2D | |
| SCHEMBL4578114 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AEPHX2CYP4F2 | |
| SCHEMBL8036310 | 0.77 | MTNR1A (0.40) | CYP4F2CYP4A11RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563347-A | Vasopressin V1a antagonists | VANTIA LTD (GB) | 2009-10-21 | — | — | CN | disclosed |