Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937372 | 0.77 | SLC1A3 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL13623382 | 0.73 | CA1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6005733 | 0.70 | ACP1 (0.50) | NPSR1SLC1A3SLC1A2MMP2MMP9 | |
| SCHEMBL12054700 | 0.70 | CA1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL31027115 | 0.70 | CYP1A2 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15880574 | 0.70 | CA1 (0.68) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3458223 | 0.70 | KIF11 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15761593 | 0.68 | PPARG (0.58) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL17679449 | 0.67 | CA1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29213152 | 0.67 | SMN1; SMN2 (0.49) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490077-A | Sulphonylaminocarbonyl derivatives of bile acid amides for use as immunomodulators | NOVARTIS AG (CH) | 2009-07-22 | — | — | CN | disclosed |