Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27768325 | 0.92 | LMNA (0.53) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL27789664 | 0.87 | MAPT (0.48) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL25337392 | 0.87 | MAPT (0.51) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL28114539 | 0.80 | RAB9A (0.53) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL9976036 | 0.80 | LMNA (0.68) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL13426507 | 0.75 | LMNA (0.69) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL15472022 | 0.75 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL12371178 | 0.75 | TSHR (0.49) | LMNAALDH1A1HPGDKDM4EGAA | |
| SCHEMBL28944524 | 0.74 | AR (0.49) | LMNAALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL20239625 | 0.74 | NR1H2 (0.49) | LMNAALDH1A1HPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572381-C | Pyrazolonaphthyridine derivative | ASKA PHARM CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |