Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 13/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71218 | 0.89 | ESRRA (0.47) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL30398916 | 0.88 | ESRRA (0.46) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL12571597 | 0.84 | CA12 (0.55) | ESRRAMIFCA1CA2CA9 | |
| SCHEMBL27768462 | 0.81 | ESRRA (0.71) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL2113115 | 0.81 | NPC1 (0.51) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL1083385 | 0.81 | ESRRA (0.43) | ESRRAMIFCA1CA2CA4 | |
| SCHEMBL71676 | 0.80 | RIPK1 (0.49) | MIF | |
| SCHEMBL27768480 | 0.80 | ESRRA (0.53) | ESRRACA1CA2CA4CA9 | |
| SCHEMBL369905 | 0.76 | MIF (0.44) | MIFCA1CA2CA9CYP2A6 | |
| SCHEMBL368478 | 0.76 | DDT (0.47) | MIFGRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |