Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 8/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789986 | 0.80 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL27789962 | 0.80 | ELANE (0.33) | ELANEPLAUHTTF2CTRB1 | |
| SCHEMBL27768658 | 0.79 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL2010275 | 0.79 | PTGS1 (0.55) | PTGS1PTGS2KDM4EMAPTABCB11 | |
| SCHEMBL15062738 | 0.77 | — | — | |
| SCHEMBL15062741 | 0.77 | — | — | |
| SCHEMBL15062652 | 0.76 | — | — | |
| SCHEMBL27789992 | 0.76 | DAO (0.34) | KDM4ETP53GAAMAPTHTT | |
| SCHEMBL5559667 | 0.74 | PTGS2 (0.35) | PTGS1PTGS2KDM4ETP53GAA | |
| SCHEMBL5560264 | 0.74 | PTGS2 (0.35) | PTGS1PTGS2ELANEPLAUKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |