Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789956 | 0.88 | PLA2G2A (0.48) | PLA2G2AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL27789996 | 0.85 | PLA2G2A (0.40) | PLA2G2AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL27889115 | 0.83 | PLA2G2A (0.40) | PLA2G2AALOX5APKDM4EALDH1A1MAPT | |
| SCHEMBL27768508 | 0.83 | PLA2G2A (0.40) | PLA2G2AS1PR3BRD4 | |
| SCHEMBL27790037 | 0.81 | KDM4E (0.39) | ALOX5APKDM4EALDH1A1MAPTHTT | |
| SCHEMBL27768470 | 0.81 | S1PR3 (0.41) | PLA2G2AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL27789959 | 0.81 | L3MBTL1 (0.44) | PLA2G2AKDM4EALDH1A1MAPTHTT | |
| SCHEMBL2012434 | 0.80 | PLA2G2A (0.40) | PLA2G2AALOX5APKDM4EALDH1A1MAPT | |
| SCHEMBL2005751 | 0.78 | PLA2G2A (0.46) | PLA2G2AALOX5APKDM4EALDH1A1MAPT | |
| SCHEMBL27789955 | 0.72 | PLA2G2A (0.60) | PLA2G2AKDM4EALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |