Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | ENPP3 | O14638 | 4/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062621 | 0.83 | CES1 (0.38) | ENPP3ENPP1MEN1KMT2ARAB9A | |
| SCHEMBL27768691 | 0.82 | CYP3A4 (0.47) | RAB9AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9882827 | 0.82 | HSD17B1 (0.46) | HSD11B1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL6821852 | 0.81 | HDAC1 (0.37) | ENPP3ENPP1MEN1KMT2ARAB9A | |
| SCHEMBL5945888 | 0.80 | HSD17B1 (0.45) | HSD11B1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL5638774 | 0.78 | ENPP3 (0.59) | ENPP3ENPP1RAB9AALDH1A1MAPT | |
| SCHEMBL15062513 | 0.77 | KDM4E (0.48) | RAB9ACES1ALDH1A1MAPTHPGD | |
| SCHEMBL6594295 | 0.73 | AKR1B1 (0.49) | HSD11B1ENPP3ENPP1MEN1KMT2A | |
| SCHEMBL278182 | 0.71 | ENPP3 (0.69) | HSD11B1ENPP3ENPP1MEN1KMT2A | |
| Benzene SCHEMBL16781371 | 0.71 | ENPP3 (0.69) | HSD11B1ENPP3ENPP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102605034-B | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2014-05-14 | — | — | CN | disclosed |
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-102605034-A | Biological enzyme resolution method for preparing optically pure (S)-5-(4-fluorophenyl)-5-hydroxypentanoate | CHONGQING HUIJIAN BIOLOG TECHNOLOGY CO LTD | 2012-07-25 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |