Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782247 | 0.93 | NR1H4 (0.53) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL1326759 | 0.89 | NR1H4 (0.57) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL29518574 | 0.85 | NR1H4 (0.53) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL31323246 | 0.85 | NPC1 (0.60) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL27789974 | 0.83 | MAPT (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2S1PR1 | |
| SCHEMBL28816316 | 0.82 | NOTUM (0.51) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL2563085 | 0.81 | GAA (0.68) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL27768478 | 0.81 | CHRNB2 (0.63) | NPC1RAB9AALDH1A1SMN1; SMN2NFKB1 | |
| SCHEMBL6207156 | 0.80 | ALDH1A1 (0.51) | NR1H4NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL6635027 | 0.80 | HPGD (0.54) | NR1H4NOTUMALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |