Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 16/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780460 | 0.89 | NAMPT (0.49) | MMP1CCR1KCNH2NAMPTLIPE | |
| SCHEMBL2776032 | 0.88 | NAMPT (0.50) | MMP1CCR1NAMPTLIPE | |
| SCHEMBL2777053 | 0.86 | CCR1 (0.48) | MMP1CCR1KCNH2 | |
| SCHEMBL2774358 | 0.86 | LIPE (0.59) | MMP1NAMPTLIPE | |
| SCHEMBL2779327 | 0.85 | DPP4 (0.46) | MMP1NAMPTLIPE | |
| SCHEMBL2774923 | 0.84 | HRH3 (0.46) | MMP1CCR1KCNH2NAMPTLIPE | |
| SCHEMBL2775119 | 0.84 | CCR1 (0.57) | CCR1KCNH2 | |
| SCHEMBL2775696 | 0.83 | EPHX2 (0.53) | CCR1KCNH2NAMPT | |
| SCHEMBL2777388 | 0.83 | KMT2A (0.43) | CCR1KCNH2NAMPT | |
| SCHEMBL2776784 | 0.82 | CHRM4 (0.45) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |