Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776334 | 0.89 | HMOX1 (0.53) | CCR1KCNH2 | |
| SCHEMBL2778165 | 0.89 | CCR1 (0.48) | CCR1KCNH2 | |
| SCHEMBL2776929 | 0.87 | LMNA (0.48) | CCR1KCNH2 | |
| SCHEMBL2779821 | 0.87 | CCR1 (0.47) | CCR1KCNH2 | |
| SCHEMBL2776856 | 0.86 | MMP1 (0.59) | CCR1KCNH2MMP1 | |
| SCHEMBL2776253 | 0.86 | LIPE (0.45) | CCR1KCNH2 | |
| SCHEMBL2776114 | 0.85 | ACACB (0.46) | CCR1KCNH2 | |
| SCHEMBL2776637 | 0.84 | CCR1 (0.45) | CCR1KCNH2 | |
| SCHEMBL2777506 | 0.83 | ALDH1A1 (0.44) | CCR1KCNH2 | |
| SCHEMBL2774934 | 0.83 | CCR1 (0.46) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |