Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | CCR1 | P32246 | 9/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776032 | 0.89 | NAMPT (0.50) | NAMPTCCR1MMP1LIPEHRH3 | |
| SCHEMBL2776856 | 0.89 | MMP1 (0.59) | NAMPTCCR1MMP1LIPEKCNH2 | |
| SCHEMBL2774358 | 0.88 | LIPE (0.59) | NAMPTMMP1LIPEHRH3 | |
| SCHEMBL2779327 | 0.87 | DPP4 (0.46) | NAMPTMMP1LIPEHRH3ACACB | |
| SCHEMBL2774923 | 0.86 | HRH3 (0.46) | NAMPTCCR1MMP1LIPEKCNH2 | |
| SCHEMBL2775696 | 0.85 | EPHX2 (0.53) | NAMPTCCR1KCNH2KMT2A | |
| SCHEMBL2777388 | 0.84 | KMT2A (0.43) | NAMPTCCR1KCNH2HRH3KMT2A | |
| SCHEMBL2776784 | 0.84 | CHRM4 (0.45) | NAMPTACACB | |
| SCHEMBL2774207 | 0.83 | NAMPT (0.49) | NAMPTMMP1LIPEHRH3 | |
| SCHEMBL2774679 | 0.83 | EPHX2 (0.51) | NAMPTCCR1KCNH2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |