Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289733 | 0.88 | KDM1A (0.41) | KDM1AMAOBTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL19130585 | 0.88 | KDM1A (0.41) | KDM1AMAOBTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL3053835 | 0.77 | KDM1A (0.43) | KDM1AMAOBTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL6946652 | 0.73 | SIGMAR1 (0.55) | KDM1AMAOBSIGMAR1 | |
| SCHEMBL19130584 | 0.73 | HDAC9 (0.50) | KDM1AMAOBTDP1ALDH1A1TP53 | |
| SCHEMBL5796055 | 0.73 | HDAC9 (0.50) | KDM1AMAOBTDP1ALDH1A1TP53 | |
| SCHEMBL7171860 | 0.71 | PDK2 (0.43) | SIGMAR1TSHR | |
| SCHEMBL6285519 | 0.70 | HDAC4 (0.44) | KDM1AMAOBTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL9652648 | 0.69 | SIGMAR1 (0.35) | KDM1AMAOBTDP1MAPK1SMN1; SMN2 | |
| SCHEMBL2267707 | 0.69 | SIGMAR1 (0.54) | SIGMAR1TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489984-A | Aminoindan derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-07-22 | — | — | CN | disclosed |