Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.47 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774296 | 0.77 | LCK (0.58) | LCK | |
| SCHEMBL771512 | 0.75 | LCK (0.70) | LCKCISD2ALDH1A1 | |
| SCHEMBL27562367 | 0.71 | LCK (0.50) | LCKCISD2 | |
| SCHEMBL27872725 | 0.70 | POLB (0.33) | — | |
| SCHEMBL2439830 | 0.69 | GPR35 (0.33) | — | |
| SCHEMBL14568752 | 0.69 | LCK (0.76) | LCK | |
| SCHEMBL6057945 | 0.68 | LCK (0.56) | LCK | |
| SCHEMBL15846534 | 0.68 | LCK (0.51) | LCK | |
| SCHEMBL6058429 | 0.68 | LCK (0.61) | LCK | |
| SCHEMBL6057789 | 0.67 | POLB (0.45) | LCKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101481359-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-07-15 | — | — | CN | disclosed |