Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 7/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | KDM1A | O60341 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153202 | 1.00 | ADAMTS5 (0.79) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL30876659 | 0.95 | ADAMTS5 (0.83) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL24634657 | 0.95 | ADAMTS5 (0.83) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL27768738 | 0.91 | HSP90AA1 (0.71) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL609006 | 0.91 | ADAMTS5 (0.84) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL23792594 | 0.91 | HSP90AA1 (0.75) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL27768660 | 0.91 | HSP90AA1 (0.75) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL2153116 | 0.90 | HSP90AA1 (0.76) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL31533556 | 0.89 | HSP90AA1 (0.66) | ADAMTS5NPC1RAB9AKMT2ALMNA | |
| SCHEMBL31533543 | 0.89 | HSP90AA1 (0.68) | ADAMTS5NPC1RAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | UNIV OSAKA (JP) | 2026-04-16 | — | — | US | disclosed |
| EP-4599832-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | OSAKA UNIVERSITY (JP) | 2025-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103444-A1 | 8-HYDROXYQUINOLINE COMPOUND AND USE THEREOF | MYLK2, MYLK, ATP2A1 | ADAMTS5 4073/4885NPC1 2505/4885RAB9A 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.