Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | GLI1 | P08151 | 1/20 | 0.38 |
| ▸ | GLI2 | P10070 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4772243 | 0.88 | GAA (0.54) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL27762029 | 0.83 | ABCB11 (0.54) | KDM4EGAAHPGDGLATP53 | |
| SCHEMBL11667064 | 0.79 | GSK3B (0.54) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| Chlorobenzene SCHEMBL5800449 | 0.78 | GAA (0.45) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL8352133 | 0.76 | KDM4E (0.51) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL13384028 | 0.74 | PTGS1 (0.52) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL4157986 | 0.73 | AKR1C2 (0.57) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL5193988 | 0.72 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL31498190 | 0.72 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL27626028 | 0.72 | NR4A2 (0.65) | KDM4EGAAALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |