Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL5800449 | 0.89 | GAA (0.45) | GAAHSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL27768656 | 0.88 | KDM4E (0.49) | GAAHSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL8352133 | 0.86 | KDM4E (0.51) | GAAHSD17B10KDM4EMAPTHTT | |
| SCHEMBL4157986 | 0.82 | AKR1C2 (0.57) | GAAHSD17B10TDP1HTR1DMAPK1 | |
| SCHEMBL28834590 | 0.80 | GAA (0.53) | GAAHSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL11667064 | 0.79 | GSK3B (0.54) | GAAHSD17B10CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL27905704 | 0.79 | GAA (0.58) | GAAHSD17B10TDP1KDM4EMAPT | |
| SCHEMBL27762029 | 0.74 | ABCB11 (0.54) | GAACYP2C9MAPK1KDM4ETP53 | |
| SCHEMBL7835698 | 0.73 | GAA (0.76) | GAAHSD17B10TDP1CYP3A4CYP1A2 | |
| SCHEMBL3385819 | 0.72 | GAA (0.66) | GAAHSD17B10TDP1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |
| EP-1931632-A2 | USEFUL INDOLE COMPOUNDS | Microbia Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |