SCHEMBL27768690

SCHEMBL27768690

CCOC(=S)SC(=O)CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
CYP2D6 P10635 1/20 0.50
SOAT1 P35610 1/20 0.42
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
GAA P10253 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
HDAC3 O15379 2/20 0.37
HDAC4 P56524 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC7 Q8WUI4 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC10 Q969S8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6291297 0.83 ALDH1A1 (0.47) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL4254370 0.81 ALDH1A1 (0.46) ALDH1A1CYP2D6LMNAHSD17B10CA1
SCHEMBL3588443 0.80 ALDH1A1 (0.50) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL10963692 0.79 ALDH1A1 (0.52) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL8844675 0.79
SCHEMBL28393816 0.74 ALDH1A1 (0.47) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL28299383 0.73 ALDH1A1 (0.39) ALDH1A1CYP2D6LMNAGAAALOX15
SCHEMBL28460835 0.72 ALDH1A1 (0.46) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL7197331 0.72 ALDH1A1 (0.50) ALDH1A1CYP2D6SOAT1LMNAHSD17B10
SCHEMBL17085768 0.72 ALDH1A1 (0.46) ALDH1A1CYP2D6SOAT1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108892745-A A kind of synthetic phospholipid and preparation method thereof with close supercritical carbon dioxide performance 东南大学 2018-11-27 CN disclosed
CN-101563377-A Block copolymer, process for making the same, and use in emulsions RHODIA OPERATIONS (FR) 2009-10-21 CN disclosed