Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844675 | 0.82 | — | — | |
| SCHEMBL10963692 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2D6CA12CA1CA2 | |
| Dixanthogen SCHEMBL37053 | 0.81 | ALDH1A1 (0.50) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL27768690 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL27661225 | 0.79 | — | — | |
| SCHEMBL411100 | 0.79 | — | — | |
| Dixanthogen SCHEMBL11408546 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP2D6CA12CA1CA2 | |
| Dixanthogen SCHEMBL1415905 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL16674835 | 0.77 | — | — | |
| SCHEMBL7280614 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274876-A1 | Process for preparing bis(ethoxythiocarbonyl)sulfide | PFIZER INC. (US) | 1988-07-20 | — | — | EP | claimed |
| CN-115181042-B | Method for preparing di (alkoxythiocarbonyl) thioether compound and preparing cyanuric acid compound simultaneously and application thereof | 中南大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-115181042-A | Method for preparing di (alkoxy thiocarbonyl) thioether compound and co-producing tristhiocyanoic acid compound and application | 中南大学 | 2022-10-14 | — | — | CN | disclosed |
| US-20100016287-A1 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF\ | GLAXO GROUP LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-1751163-A2 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005118549-A2 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |
| EP-1023277-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999018093-A1 | NOVEL 3,4-DIARYLTHIAZOLIN-2-ONE OR -2-THIONE DERIVATIVES, PREPARATION METHODS AND USES IN THERAPY | LABORATOIRES UPSA (FR) | 1999-04-15 | — | — | WO | disclosed |
| US-5859036-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATORIES UPSA (FR) | 1999-01-12 | — | — | US | disclosed |
| EP-0274876-B1 | PROCESS FOR PREPARING BIS(ETHOXYTHIOCARBONYL)SULFIDE | PFIZER INC. (US) | 1991-01-30 | — | — | EP | disclosed |
| EP-0274876-A1 | Process for preparing bis(ethoxythiocarbonyl)sulfide | PFIZER INC. (US) | 1988-07-20 | — | — | EP | disclosed |
| EP-0274876-A1 | Process for preparing bis(ethoxythiocarbonyl)sulfide | PFIZER INC. (US) | 1988-07-20 | — | — | EP | disclosed |
| EP-0274876-A1 | Process for preparing bis(ethoxythiocarbonyl)sulfide | PFIZER INC. (US) | 1988-07-20 | — | — | EP | disclosed |
| US-3976769-A | INSECTICIDE | AIRWICK INDUSTRIES, INC. (US) | 1976-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016287-A1 | COMPOUNDS HAVING AFFINITY FOR DOPAMINE D3 RECEPTOR AND USES THEREOF\ | DRD3, DRD2, SLC6A3 | ALDH1A1 941/4885CYP2D6 301/4885CA12 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.