Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785020 | 0.85 | MAPT (0.51) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL3355607 | 0.85 | HTR7 (0.49) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL29167245 | 0.85 | MAPT (0.51) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL16371052 | 0.85 | PLG (0.46) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL30672928 | 0.85 | PLG (0.46) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL3808256 | 0.84 | KRAS (0.52) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL23902730 | 0.82 | GLS (0.46) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL2263041 | 0.82 | GLS (0.46) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL30241520 | 0.82 | GLS (0.46) | KRASPLGPLAUHTR7SLC6A2 | |
| SCHEMBL2479169 | 0.82 | HTR7 (0.47) | KRASPLGPLAUHTR7SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466709-B | 1,5 and 3, 6-substituted indole compounds having NOS inhibitory activity | NEURAXON INC | 2013-03-20 | — | — | CN | disclosed |
| CN-101466709-A | 1, 5 and 3, 6-substituted indole compounds having NOS inhibitory activity | NEURAXON INC (CA) | 2009-06-24 | — | — | CN | disclosed |