Biphenyl

Biphenyl

SCHEMBL27769451

CCOB(O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 1/20 0.43
ALDH1A1 P00352 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
MAPT P10636 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
TAAR1 Q96RJ0 1/20 0.39
HPGD P15428 3/20 0.38
KDM4E B2RXH2 3/20 0.37
USP2 O75604 1/20 0.37
MMP3 P08254 1/20 0.37
BCL2L1 Q07817 1/20 0.37
PCSK9 Q8NBP7 1/20 0.36
LSS P48449 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27976178 0.86 MGLL (0.43) MGLLCA1CA2ALDH1A1SMN1; SMN2
SCHEMBL28492929 0.83 PCSK9 (0.34) CA1CA2ALDH1A1SMN1; SMN2L3MBTL1
Biphenyl SCHEMBL27790914 0.79 PCSK9 (0.48) ALDH1A1SMN1; SMN2L3MBTL1HPGDPCSK9
Biphenyl SCHEMBL1147617 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1
Biphenyl SCHEMBL8192900 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1
Biphenyl SCHEMBL5898513 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1
Biphenyl SCHEMBL51202 0.78 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1
SCHEMBL163658 0.77
Biphenyl SCHEMBL10601883 0.76 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2MAPTL3MBTL1NPC1
Biphenyl SCHEMBL27769448 0.75 MGLL (0.50) MGLLCA1CA2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101633704-B Catalyst component used for ethylene polymerization reaction and catalyst thereof SINOPEC CORP. (CN) 2011-12-28 CN disclosed
CN-101633704-A Catalyst component used for ethylene polymerization reaction and catalyst thereof CHINA PETROLEUM & CHEMICAL 2010-01-27 CN disclosed