Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133635 | 0.78 | P2RX4 (0.41) | P2RX4MTNR1AMTNR1BLMNATSHR | |
| Hydrochloric Acid SCHEMBL3122652 | 0.77 | P2RX4 (0.40) | USP2P2RX4MTNR1AMTNR1BLMNA | |
| Hydrochloric Acid SCHEMBL29383470 | 0.77 | P2RX4 (0.40) | USP2P2RX4MTNR1AMTNR1BLMNA | |
| SCHEMBL20987115 | 0.73 | MAPK1 (0.35) | HRH1SLC6A2HTR2ASLC6A4DRD3 | |
| SCHEMBL7239877 | 0.69 | SMN1; SMN2 (0.60) | TDP1NPC1LMNATSHR | |
| SCHEMBL9030241 | 0.68 | P2RX4 (0.37) | P2RX4LMNAMAPK1 | |
| SCHEMBL1989267 | 0.68 | MEN1 (0.42) | USP2TDP1P2RX4NPC1LMNA | |
| SCHEMBL9030962 | 0.68 | MAPT (0.38) | TDP1P2RX4NPC1MTNR1AMTNR1B | |
| SCHEMBL27498070 | 0.68 | KMT2A (0.41) | P2RX4LMNASCN9A | |
| SCHEMBL21071084 | 0.67 | SMN1; SMN2 (0.57) | TDP1NPC1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479008-A | Benza -oxyacetic acid derivatives as PPAR-delta agonists for raising HDL-C, lowering LDL-C and lowering cholesterol | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-08 | — | — | CN | disclosed |